Occupational and Environmental Medicine 1995;52:621-624 Fibrogenic effect of woliastonite compared with asbestos dust and dusts
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چکیده
a day, 5 days a week for 12 months plus 12 months observation, or for a full 24 months) inhalation exposure of wollastonite in rats (McConnell et al, 1991), I was surprised to find the authors of this article reporting pulmonary fibrosis after intratracheal (IT) instillation. I offer the following comments and possible explanation for this unexpected result. It is difficult to determine from the report what their rats were actually exposed to or the total exposure. The authors reported that they obtained their wollastonite sample by "mechanical treatment (crushing, sedimentation, etc)" and reported a geometric
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Occupational and Environmental Medicine 1995;52:621-624 Fibrogenic effect of woliastonite compared with asbestos dust and dusts
a day, 5 days a week for 12 months plus 12 months observation, or for a full 24 months) inhalation exposure of wollastonite in rats (McConnell et al, 1991), I was surprised to find the authors of this article reporting pulmonary fibrosis after intratracheal (IT) instillation. I offer the following comments and possible explanation for this unexpected result. It is difficult to determine from th...
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